TFEC Antibody, Biotin conjugated

Code CSB-PA023430LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TFEC Polyclonal antibody
Uniprot No.
Target Names
TFEC
Alternative Names
bHLHe34 antibody; Class E basic helix-loop-helix protein 34 antibody; hTFEC-L antibody; TCFEC antibody; TFE-C antibody; Tfec antibody; TFEC protein antibody; TFEC_HUMAN antibody; TFECL antibody; Transcription factor EC antibody; Transcription factor EC-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription factor EC protein (1-197AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
Gene References into Functions
  1. Two alternatively spliced TFEC isoforms have been found to be sequence-specific transcriptional activators of the nonmuscle myosin II heavy chain-A gene in transfected cells. PMID: 11467950
Subcellular Location
Nucleus.
Protein Families
MiT/TFE family
Tissue Specificity
Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
Database Links

HGNC: 11754

OMIM: 604732

KEGG: hsa:22797

STRING: 9606.ENSP00000265440

UniGene: Hs.125962

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